Roseanne Arnold

(Roseanne Conner)

John Goodman

(Dan Conner)

Laurie Metcalf

(Jackie Harris)

Lecy Goranson

(Becky Conner-Healy)

Sara Gilbert

(Darlene Conner)

Michael Fishman

(D.J. Conner)

Natalie West

(Crystal Anderson Conner)

Elizabeth Franz

(Marsha)

Lori Tan Chinn

(Iris)

Melora Walters

(Debbie)

Nancy Lenehan

()