Roseanne Arnold

(Roseanne Conner)

John Goodman

(Dan Conner)

Lecy Goranson

(Becky Conner-Healy)

Sara Gilbert

(Darlene Conner)

Michael Fishman

(D.J. Conner)

Laurie Metcalf

(Jackie Harris)

Natalie West

(Crystal Anderson Conner)

Bonnie Sheridan

(Bonnie Watkins)

Martin Mull

(Leon Carp)

Stephen Taylor Knot

(Child)

Lee Garlington

(Karen Miller)

Walter Jacobson

(Walter)