Roseanne Arnold

(Roseanne Conner)

John Goodman

(Dan Conner)

Laurie Metcalf

(Jackie Harris)

Lecy Goranson

(Becky Conner-Healy)

Sara Gilbert

(Darlene Conner)

Michael Fishman

(D.J. Conner)

Glenn Quinn

(Mark Healy)

Johnny Galecki

(David Healy)

Natalie West

(Crystal Anderson Conner)

Carl Franklin

(Gil)

Don Opper

()

Max Brooks

()