Johnny Galecki

(Leonard Hofstadter)

Jim Parsons

(Sheldon Cooper)

Kaley Cuoco

(Penny)

Simon Helberg

(Howard Wolowitz)

Kunal Nayyar

(Raj Koothrappali)

Mayim Bialik

(Amy Farrah Fowler)

Melissa Rauch

(Bernadette Rostenkowski)

Carol Ann Susi

(Debbie Wolowitz)

Casey Sander

(Mike Rostenkowski)

Christopher Neiman

(Dr. Dreyfus)

Mike Massimino

(Michael Massimino)