Samantha Morton

(Catherine De Medici)

Charles Dance

(Pope Clement)

Amrita Acharia

(Aabis)

Colm Meaney

(King Francis)

Barry Atsma

(Montmorency)

Adam Garcia

()

Raza Jaffrey

(Francois Guise)

Naomi Battrick

(Anna D'Etampes)

Ray Panthaki

(Charles Guise)

Enzo Cilenti

(Ruggieri)

Nicholas Burns

(Antoine de Bourbon)

Sennia Nanua

(Rahima)

Danny Kirrane

(Louis de Bourbon)

Rebecca Gethings

(Queen Eleanor)

Liv Hill

(Young Catherine)

Kiruna Stamell

(Mathilde)

Antonia Clarke

(Mary Queen of Scots)

George Jaques

(Francis II)

Jade Croot

(Edith)