Ellen Burstyn

(Chris MacNeil)

Linda Blair

(Regan Teresa MacNeil)

Max von Sydow

(Father Lankester Merrin)

Lee J. Cobb

(Lieutenant William Kinderman)

Kitty Winn

(Sharon Spencer)

Jack MacGowran

(Burke Dennings)

Jason Miller

(Father Damien Karras)

William O'Malley

(Father Dyer)

Barton Heyman

(Dr. Klein)

Pete Masterson

(Dr. Barringer, Clinic Director)

Rudolf Schündler

(Karl)

Gina Petrushka

(Willi)

Robert Symonds

(Dr. Taney)

Arthur Storch

(Psychiatrist)

Thomas Bermingham

(Tom, President of University)

Vasiliki Maliaros

(Karras' Mother)

Titos Vandis

(Karras' Uncle)

Wallace Rooney

(Bishop Michael)

Ron Faber

(Chuck, Assistant Director/Demonic Voice)

Donna Mitchell

(Mary Jo Perrin)

Roy Cooper

(Jesuit Dean)

Robert Gerringer

(Senator at Party)

Mercedes McCambridge

(Pazuzu)