Denzel Washington

(Frank Lucas)

Russell Crowe

(Richie Roberts)

Chiwetel Ejiofor

(Huey Lucas)

Cuba Gooding

(Nicky Barnes)

Josh Brolin

(Detective Trupo)

Ted Levine

(Lou Toback)

Armand Assante

(Dominic Cattano)

RZA

(Moses Jones)

John Ortiz

(Javier J. Rivera)

John Hawkes

(Freddie Spearman)

Roger Guenveur Smith

(Nate)

Ruby Dee

(Mama Lucas)

Idris Elba

(Tango)

Carla Gugino

(Laurie Roberts)

Yul Vazquez

(Alfonse Abruzzo)

Ruben Santiago-Hudson

(Doc)

Joe Morton

(Charlie Williams)