Steve Carell

(Gru)

Jason Segel

(Vector)

Russell Brand

(Dr. Nefario)

Julie Andrews

(Gru's Mom)

Will Arnett

(Mr. Perkins)

Kristen Wiig

(Miss Hattie)

Miranda Cosgrove

(Margo)

Dana Gaier

(Edith)

Elsie Fisher

(Agnes)