Andrew Garfield

(Spider-Man/Peter Parker)

Emma Stone

(Gwen Stacy)

Rhys Ifans

(The Lizard/Dr. Curt Connors)

Denis Leary

(Capt. Stacy)

Campbell Scott

(Richard Parker)

Irrfan Khan

(Rajit Ratha)

Martin Sheen

(Uncle Ben)

Sally Field

(Aunt May)

Embeth Davidtz

(Mary Parker)

Chris Zylka

(Flash Thompson)

Max Charles

(Peter Parker Age 4)

C. Thomas Howell

(Jack's Father)

Jake Ryan Keiffer

(Jack)

Kari Coleman

(Helen Stacy)