Alec Baldwin

(Theodore Templeton)

James Marsden

(Tim Templeton)

Eva Longoria

(Carol Templeton)

Jeff Goldblum

(Dr. Armstrong)

Ariana Greenblatt

(Tabitha)

Jimmy Kimmel

(Ted Templeton)

Lisa Kudrow

(Janice Templeton)

Amy Sedaris

(Tina Templeton/Boss Baby)