Noah Wyle

(Dr. Michael "Robby" Robinavitch)

Tracy Ifeachor

(Dr. Heather Collins)

Fiona Dourif

(Dr. McKay)

Taylor Dearden

(Dr. King)

Isa Briones

(Dr. Santos)

Gerran Howell

(Whitaker)

Shabana Azeez

(Javadi)

Brandon Mendez Homer

(Donnie Donahue)

Patrick Ball

(Dr. Langdon)

Katherine LaNasa

(Dana Evans)

Supriya Ganesh

(Dr. Mohan)

Amielynn Abellera

(Perlah Alawi)

Kristin Villanueva

(Princess)

Jalen Thomas Brooks

(Mateo Diaz)